casual
Active member
hahahaha suboxone isn't as addictive, hmm? You must've read that on their website...google trying to get off suboxone and read the....ohhh...I dunno, thousands of horror stories.
Also, suboxone (a formulation containing 8 mg buprenorphine and 2 mg naloxone) has an incredibly high affinity for opiate/oid receptors in the brain and is also only a partial agonist as opposed to a full like the other drugs you've mentioned (that's why it doesn't cause the same level of euphoria and isn't as likely to cause respiratory depression).
It is not the naloxone (a full on opiate atagonist) that causes the blocking effect, in fact, it has been proven that the naloxone is 100% inactive as it's binding affinity is lower than the bupes. Rather, it is the buprenorphine itself and its high affinity that prevents other opiates from working their magic at the receptor sites. The blocking effect can be overcome by simply taking more of the DOC, or by skipping a dose or two depending on dosage.
Opiates are insidious, hopelessly addicting drugs. People who go on to battle an addiction to opiates suffer a 99% relapse rate. Meaning, anyone who crosses into a state of physical and psychological dependence (anyone who will experience withdrawal upon abrupt cessation) stands only a 1% of never ending up there again. That goes for you too, OP, so I'm not sure why you're acting like you made it out and everything will be just hunky dory for ya, bud.
Also, suboxone (a formulation containing 8 mg buprenorphine and 2 mg naloxone) has an incredibly high affinity for opiate/oid receptors in the brain and is also only a partial agonist as opposed to a full like the other drugs you've mentioned (that's why it doesn't cause the same level of euphoria and isn't as likely to cause respiratory depression).
It is not the naloxone (a full on opiate atagonist) that causes the blocking effect, in fact, it has been proven that the naloxone is 100% inactive as it's binding affinity is lower than the bupes. Rather, it is the buprenorphine itself and its high affinity that prevents other opiates from working their magic at the receptor sites. The blocking effect can be overcome by simply taking more of the DOC, or by skipping a dose or two depending on dosage.
Opiates are insidious, hopelessly addicting drugs. People who go on to battle an addiction to opiates suffer a 99% relapse rate. Meaning, anyone who crosses into a state of physical and psychological dependence (anyone who will experience withdrawal upon abrupt cessation) stands only a 1% of never ending up there again. That goes for you too, OP, so I'm not sure why you're acting like you made it out and everything will be just hunky dory for ya, bud.