i'd second going and seeing what fits you the best.  some guns just don't fit some people's hands well.
for instance, glocks chew up my thumb knuckle and I personally don't really like shooting them for an extended period of time because I end up with a raw spot.  however, my baby eagle & my S&W don't give me any problems at all.  my roommate, on the other hand, absolutely loves his glock and it doesn't bite his hand even the slightest.