peyote...wow....I've done some hallucinogens in my day, but I feel like peyote is on a whole different level.
If you feel comfortable dropping a ten-strip and tripping nuts for, say, 14 to maybe 20 hours, then you might be okay. Problem is though, peyote can turn into a multi-day trip, depending on how much is consumed. Personally, there are times in an acid trip when all I want to do is be done with it...the hallucinations get so overwhelming at times that I just want it over with. Peyote is unrelenting. Frankly, I feel like it is something that should never be consumed without some sort of baby sitter.
Oh, and prepare to wretch your guts out a little while after you've consumed.