there's been talks about cascadia for years... for everyone who lives within the boarders of this "Cascadia", it would be a blessing... for those who fall outside it's boarders it would be bad.
With California included Cascadia (Alaska, Yukon, BC, Alberta, Washington, Idaho, Oregon, and California) would have a higher GDP (or whatever it is) than the US and Canada. It would be the new powerhouse of the world, we'd have all the natural resources and water, the population, and the culture to slow down the destruction of our environment.
But if you think there's a chance in hell the U.S. would allow the PNW to secede you've gotta be joking. We will see the North American Union before we see Cascadia.