Accutane is the answer. I had horrible acne from about 6th-7th grade until 11th grade. I tried everything that exists. Proactiv and its knock-offs, all kinds of washes, prescription stuff, even this eBay stuff. Nothing worked. Then I finally got accutane. It is the best, and ONLY thing that worked for me. I was on it for 5.5 months. Yes, it was horrible. It was during ski season and my knees, hips and back would alwasy be sore because it messes with your joints. I had the worst dry skin. I would put lotion on 10 times a day. It dried the shit out of my lips. I was constipated a lot and shit. I got rashes on the tops of my hands sometimes, and the inside of my arms. There might even be more that I'm forgetting. BUT even with all that, I WOULD DO IT AGAIN IN A HEARTBEAT. Because the shit actually worked. It's been over a year now and I am still fine. All my side effects went away within a few days.  All I do now is wash my face with some regular cleansing face wash.
The only regret I have is that I didn't do it sooner instead of living with it on my conscience all those years. I would suggest it to anyone who has acne. If your doctor says you can take it, do it.
Also, about the liver stuff. I was always fine. I smoked, but held off on drinking a lot, and was fine. Two of my friends who also did it got wasted all the time and never had any liver problems.