6. a drug inhibits the uptake or reabsorption of water by the distal convoluted tubules. what effect would this drug have on urine output, urine concentration, blood pressure, blood volume, and the concentration of blood
If the uptake/ reabsorption of water is compromised, then the loop of henle will not be able to reabsorb water for re-uptake by the blood. This would result in more dilute urine (remember it's the concentration of solute in solution that gives concentration; more water & same amount of solute = less concentrated solution)If uptake/reabsorption is compromised, then as stated above, urine output would be greater, otherwise there would be no effect on concentration.
If water is not reabsorbed and returned to the blood, then blood volume would decrease as would blood pressure by the aforementioned principles.
Concentration of blood would increase minimally.