Not really a proven way to prevent acl injuries. You should definitely make sure your muscles are working strong and anytime you feel weakness in your legs just stop with the big stuff for the day. Warm up well. Most injuries happen at the beginning or end of day when you are either not warmed up, or too tired already.
There is some research that your hamstring to quad ratio should be higher, 1:1 is best. Most people have much stronger quads, so make your hamstrings stronger.
As for general wear and tear of the knee - that's inevitable if you do lots of sports in your life. As you get older you can do more stretching, pilates, physio etc to relieve the pain and keep your joints working smoothly.